My previous system was a Linux-box. I made some adjustments to my keyboard in order to make it “better”. Since I use Vim a lot (apologies to Emacs-fans), the escape-key is doing overtime. On a normal keyboard however, the escape-key is located at the top left. Other keys are very near the main keyboard, but are hardly used. I almost never use the CapsLock key at all. So I switched both keys around, giving the CapsLock key the escape-function and the other way around.
Under Linux, you can remap keys using. It seems that Windows has a similar feature, although much less documented. Here is a short summary of .